La Famosa 21 was a Mexican radio station based in Mexico City, operating on AM frequency 1440 kHz. It was known for its tropical and regional Mexican music format, catering to a diverse audience. The station's official callsign was XEEST-AM, and it was part of Grupo Radiorama. In 2020, the station underwent a format change and ceased to operate under the "La Famosa 21" brand. Its frequency was later repurposed for a new format under different branding.